2025-26 Men’s First Round Odds: Spreads, Lines for all 32 Games
Let’s get down to business.
Check out the odds for every first-round game in the men’s NCAA Tournament at DraftKings Sportsbook as of March 20.
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THURSDAY, MARCH 19
No. 16 Siena 65, No. 1 Duke 71
Spread: Duke -28.5 (Siena covers)
O/U: 136.5 (Under hits)
No. 16 Howard 80, No. 1 Michigan 101
Spread: Michigan -30.5 (Howard covers)
O/U: 151.5 (Over hits)
No. 15 Idaho 47, No. 2 Houston 78
Spread: Houston -23.5 (Houston covers)
O/U: 137.5 (Under hits)
No. 14 Kennesaw State 64, No. 3 Gonzaga 73
Spread: Gonzaga -21.5 (Kennesaw State covers)
O/U: 152.5 (Under hits)
No. 14 North Dakota State 67, No. 3 Michigan State 92
Spread: Michigan State -15.5 (MSU covers)
O/U: 143.5 (Over hits)
No. 14 Penn 70, No. 3 Illinois 105
Spread: Illinois -25.5 (Illinois covers)
O/U: 151.5 (Over hits)
No. 13 Troy 47, No. 4 Nebraska 76
Spread: Nebraska -13.5 (Nebraska covers)
O/U: 139.5 (Under hits)
No. 13 Hawaii 78, No. 4 Arkansas 97
Spread: Arkansas -15.5 (Arkansas covers)
O/U: 158.5 (Over hits)
No. 12 High Point 83, No. 5 Wisconsin 82
Spread: Wisconsin -10.5 (HPU covers)
O/U: 162.5 (Over hits)
No. 12 McNeese 68, No. 5 Vanderbilt 78
Spread: Vanderbilt -12.5 (McNeese covers)
O/U: 149.5 (Under hits)
No. 11 South Florida 79, No. 6 Louisville 83
Spread: Louisville -4.5 (USF covers)
O/U: 161.5 (Over hits)
No. 11 VCU 82, No. 6 UNC 78 (OT)
Spread: UNC -2.5 (VCU covers)
O/U: 150.5 (Over hits)
No. 11 Texas 79, No. 6 BYU 71
Spread: BYU -2.5 (Texas covers)
O/U: 158.5 (Under hits)
No. 10 Texas A&M 63, No. 7 Saint Mary’s 50
Spread: Saint Mary’s -2.5 (A&M covers)
O/U: 148.5 (Under hits)
No. 9 TCU 66, No. 8 Ohio State 64
Spread: Ohio State -2.5 (TCU covers)
O/U: 146.5 (Under hits)
No. 9 Saint Louis 102, No. 8 Georgia 77
Spread: Georgia -2.5 (SLU covers)
O/U: 168.5 (Over hits)
FRIDAY, MARCH 20
No. 16 LIU vs. No. 1 Arizona
Spread: Arizona -30.5
Moneyline: Arizona -100000, LIU +5000
O/U: 149.5
No. 16 Prairie View vs. No. 1 Florida
Spread: Florida -35.5
Moneyline: Florida -100000, Prairie View +5000
O/U: 155.5
No. 15 Tennessee State vs. No. 2 Iowa State
Spread: ISU -24.5
Moneyline: ISU -8000, Tennessee State +2200
O/U: 148.5
No. 15 Queens U vs. No. 2 Purdue
Spread: Purdue -25.5
Moneyline: Purdue -8000, Queens U +2200
O/U: 162.5
No. 15 Furman vs. No. 2 UConn
Spread: UConn -20.5
Moneyline: UConn -4500, Furman +1700
O/U: 136.5
No. 14 Wright State vs. No. 3 Virginia
Spread: Virginia -18.5
Moneyline: Virginia -2800, Wright State +1300
O/U: 145.5
No. 13 Hofstra vs. No. 4 Alabama
Spread: Alabama -11.5
Moneyline: Alabama -800, Hofstra +550
O/U: 158.5
No. 13 Cal Baptist vs. No. 4 Kansas
Spread: Kansas -13.5
Moneyline: Kansas -1350, Cal Baptist +800
O/U: 138.5
No. 12 Akron vs. No. 5 Texas Tech
Spread: Texas Tech -7.5
Moneyline: Texas Tech -325, Akron +260
O/U: 155.5
No. 12 Northern Iowa vs. No. 5 St. John’s
Spread: St. John’s -9.5
Moneyline: St. John’s -535, UNI +400
O/U: 131.5
No. 11 Miami OH vs. No. 6 Tennessee
Spread: Tennessee -11.5
Moneyline: Tennessee -550, Miami OH +410
O/U: 149.5
No. 10 Missouri vs. No. 7 Miami FL
Spread: Miami -1.5
Moneyline: Miami -130, Missouri +110
O/U: 146.5
No. 10 Santa Clara vs. No. 7 Kentucky
Spread: Kentucky -3.5
Moneyline: Kentucky -155, Santa Clara +130
O/U: 157.5
No. 10 UCF vs. No. 7 UCLA
Spread: UCLA -5.5
Moneyline: UCLA -245, UCF +200
O/U: 152.5
No. 9 Utah State vs. No. 8 Villanova
Spread: Utah State -1.5
Moneyline: Utah State -125, Villanova +105
O/U: 146.5
No. 9 Iowa vs. No. 8 Clemson
Spread: Iowa -2.5
Moneyline: Iowa -130, Clemson +110
O/U: 128.5
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